Diseases

Estrogens - estradiol, estrone & estriol

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estrogens are sex hormones, which play an important role especially in the female body. They are critically involved in the menstrual cycle and reproductive system. Read more about the function of estrogens, which measurements in the blood are considered normal and what can increase or decrease the readings!

Article summaryEstrogens - estradiol, estrone & estriol

  • What are estrogens?
  • Natural and artificial estrogens
  • When are the estrogens determined?
  • Estrogens standard values
  • When are the estrogen levels too low?
  • When are the estrogen levels too high?

What are estrogens?

Estrogens are like the progesterone progesterone female sex hormones. Estrogens are mainly produced in the ovaries, in addition to small amounts in the adrenal cortex and in pregnant women in the placenta (mother cake).

Strictly speaking, the term "female" sex hormones for estrogens is not correct. Because even men produce estrogens (more precisely: estradiol), albeit only in small quantities. Educational sites are mainly the testicles.

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Natural and artificial estrogens

The most important in the body occurring (natural) estrogens are estradiol, estrone and estriol. In women, together with the progestins, they control all processes in the female cycle and in reproduction. For example, they cause the maturation of follicles in the ovaries, induce ovulation, ensure the transport of the egg through the fallopian tube into the uterus and ensure that the mucous membrane grows in the uterus. Estrogens also promote the growth of breasts and increase mucus production in the cervix.

In addition, estrogens have many effects on the metabolism: for example, they increase blood circulation, lead to the accumulation of water, promote the production of proteins and lead to an increase in triglycerides and cholesterol.

In men, too, estrogen plays a role in lipid metabolism and many other metabolic processes. In addition, they are considered an important stimulus of male sexuality.

Artificial estrogens such as ethinyl oestradiol are part of the contraceptive pill. In addition, they are used in women for the treatment of menopausal symptoms.

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When are the estrogens determined?

Estradiol is determined in the following cases:

  • in case of cycle disorders (especially bleeding disorders)
  • to determine if a woman needs hormones after menopause
  • to determine if infertility treatment is effective (sterility treatment)
  • in disorders of puberty development
  • in tumor therapy and diagnostics (in hormone-forming tumors such as ovarian cancer).
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Estrogen standard values

The estrogens are determined in the blood serum. In most cases, the most potent estrogen is estrogen. Sometimes estriol and estrone are also of interest.

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