Article overview progesterone
- What is progesterone?
- When do you determine the progesterone?
- Progesterone standard values
- When is the progesterone level too low?
- When is the progesterone level too high?
What is progesterone?
Like estrogen, progesterone is a female sex hormone, although it also occurs in the male body. It is produced in women especially in the corpus luteum (corpus luteum) and is therefore called corpus luteum hormone. The yellow body arises after each ovulation from the ruptured follicles, which remain in the ovary. Therefore, in women, the concentration of progesterone in the blood is highest in the middle luteal phase of their menstrual cycle. That's about the fifth to eighth days after ovulation.
Progesterone regulates the female cycle along with estrogens and prepares the body for pregnancy: Progesterone ensures that the egg can be fertilized and implanted in the uterine lining, that the pregnancy is preserved and the mammary glands prepare for milk secretion. Therefore, in pregnant women progesterone is also produced in the placenta.
In men and women also the adrenal cortices produce progesterone, but only in small amounts.
Progesterone produces many other hormones in the body, such as androgens, cortisol or aldosterone.
"Artificial" progesterone = progestin
There are artificially produced hormones that have similar effects to natural progesterone. These hormones are called progestins. They are found in hormone preparations that are used, for example, for birth control ("pill"), menopausal symptoms or acne.To the table of contents
When do you determine the progesterone?
Progesterone is determined, for example, in the case of unfulfilled desire for children as well as in the case of cycle disorders. It is also measured if the doctor suspects a hormonal condition. These include benign or malignant tumors that produce progesterone.To the table of contents
Progesterone standard values
Progesterone is determined in the blood serum. For Girls and women the following standard values apply (in nanomoles per liter):
Progesterone Standard Value
Before puberty (10 - 15 years)
0.48-4.45 nmol / l
0.19-2.83 nmol / l
0.38-38.2 nmol / l
5.82 - 76 nmol / l
After the menopause
<0.16-0.41 nmol / l
Pregnancy: 1st trimester
34.98 - 140.9 nmol / l
Pregnancy: 2nd trimester
80.8 - 265 nmol / l
Pregnancy: 3rd trimester
187-681 nmol / l
Conversion to nanograms per milliliter: nmol / l x 0.314 = ng / ml
at men Irrespective of the age, the progesterone norm values are <0.16 to 0.48 nmol / l.To the table of contents
When is the progesterone level too low?
Possible reasons for a decreased progesterone value are, for example:
- Disorders of ovulation (ovulation disorders), for example in a menstrual cycle without ovulation (= anovulatory cycle) or a luteal weakness (corpus luteum insufficiency)
- Underdevelopment or malformation of the ovaries (primary ovarian failure)
- Anorexia nervosa (anorexia nervosa)
- Hypofunction of the anterior pituitary (lack of FSH production)