Eva Rudolf-Müller is a freelance author at lifelikeinc.com. She studied human medicine and journalism and worked in both areas - as a doctor in the clinic, as a reviewer, as well as a medical journalist for various journals. Currently, she works in online journalism, where a wide range of medicine is offered to all.More about the lifelikeinc.com expertsreticulocytes are young, immature red blood cells (erythrocytes). They are formed in the bone marrow and flushed out into the blood. There they mature within a few days to mature cells. The proportion of reticulocytes in the blood is very small, but may increase with oxygen deficiency or after blood loss. Read when the bone marrow releases more reticulocytes and when their percentage in the blood is reduced!
- What are reticulocytes?
- When do you determine the reticulocytes?
- When are too few reticulocytes in the blood?
- When are too many reticulocytes in the blood?
- What to do if the reticulocyte value is changed?
What are reticulocytes?
Reticulocytes are red blood cells that are not fully mature. Like the mature erythrocytes, they no longer contain a cell nucleus, but still possess specific genetic information (RNA) in the cytoplasm and the endoplasmic reticulum (lat. "Rete" = net). The latter provides for certain cell metabolism processes and gives the cell interior a typical net-like appearance under the microscope. When RNA and endoplasmic reticulum have been expelled, the reticulocyte has ripened to erythrocyte.
The number of reticulocytes in the blood allows conclusions about the blood production activity of the bone marrow. It may indicate certain illnesses such as anemia (anemia) or infections. However, it also changes in lack of oxygen in the air, for example at high altitude. Also, doping to increase blood formation (such as with EPO) changes the blood formation rate.To the table of contents
When do you determine the reticulocytes?
In the following cases the reticulocytes are determined in the blood:
- in anemia (anemia)
- in therapy with iron, vitamin B12 or folic acid
- in a medically required therapy with erythropoietin (EPO)
- in blood cancer (leukemia)
- after a stem cell transplant