Article overviewCYFRA 21-1
- What is CYFRA 21-1?
- When will the CYFRA 21-1 value be determined?
- When is the CYFRA 21-1 value too low?
- When is the CYFRA 21-1 value too high?
What is CYFRA 21-1?
CYFRA 21-1 is the abbreviation for cytokeratin 19 fragment. Cytokeratins are proteins that contribute to the stabilization and shape of a cell. There are 20 known cytokeratins. Cytokeratin 19 is found mainly in the capillaries (epithelia) of the bronchial mucosa. In the blood one can measure a fragment of cytokeratin 19, the cytokeratin 19 fragment (= CYFRA 21-1).To the table of contents
When will the CYFRA 21-1 value be determined?
CYFRA 21-1 is the most important tumor marker in a specific type of lung cancer, non-small cell lung cancer. It is determined to diagnose this type of lung cancer, to control the course of the disease and therapy, and to assess the success of therapy.
The CYFRA 21-1 value is also determined for other cancers, such as bladder cancer and some benign diseases.To the table of contents
When is the CYFRA 21-1 value too low?
A downward deviation is medically not significant.To the table of contents
When is the CYFRA 21-1 value too high?
In healthy adults, serum CYFRA 21-1 levels are below 3.0 nanograms per milliliter (ng / ml). For certain cancers and some benign diseases, however, the reading may be increased, such as:
- Lung cancer (especially non-small cell lung carcinoma)
- bladder cancer
- Diseases of the gastrointestinal tract
- gynecological diseases
- urological diseases